I see patients in the relatively new subspecialty of pediatric neurointerventional radiology, an area in which we at Boston Children's Hospital have built one of the world’s largest and most comprehensive practices. My focus has been on children with neurovascular diseases and some cancers affecting the head and neck, using unique, guided approaches for treatment. I am passionate about making these novel treatment approaches, pionered for use in adults, available to children. I am dual-trained as both a physician and scientist, having obtained my medical degree from Cornell University Medical College and my doctorate from Rockefeller University, in the Laboratory of Biophysics and Neurophysiology. At New York University Medical Center, I completed residencies in neurology and diagnostic radiology and fellowships in diagnostic and interventional neuroradiology. In my role as a leader of the hospital's Cerebrovascular Surgical and Interventions Center, I see children with conditions affecting blood vessels in and around the brain and the spine. I have worked closely with colleagues from Neurosurgery and Neurology to build an internationally recognized multidisciplinary group that tightly integrates all aspects of clinical care and outcomes research. In children with intracranial and extracranial vascular anomalies, we have pioneered the use of devices developed for adults, often in creative ways different from their original designed purpose. We create precision 3D models of patients’ brains and blood vessels using data from their brain scans to help us plan procedures. We have demonstrated that it is possible to achieve high-quality image-guided treatment at low radiation doses. And new techniques are allowing us to safely access arteries even in the youngest patients. In addition, I treat patients with head and neck solid tumors, primarily retinoblastoma, at Boston Children’s Hospital and the Dana Farber Institute. Colleagues and I are exploring how we can further adapt techniques currently used in adults to help children with solid tumors, both for primary and secondary treatment, and for palliative treatment.

Alfred specializes in the endovascular and microsurgical care of patients with diseases of the blood vessels in the brain and spinal cord. To provide a comprehensive approach to these problems, he has focused his training with an emphasis on a broad range of tools and techniques as well as novel applications of combined surgeries to treat these diseases. Endovascular techniques use catheters from within the blood vessels to treat problems of the blood vessels but also to deliver medications in a very precisely targeted fashion. Microsurgical techniques allow meticulous separation of diseased blood vessels from the brain and allow reconstruction of diseased vessels as well as creation of new blood supply to the brain. Having developed this expertise, he continues to engage in research to better understand normal and abnormal blood vessels. His background in engineering leads to his emphasis on quantitative analysis of blood flow and the application of new technologies such as computational analysis and robotics.

I am a child neurologist with special interest in cerebrovascular disorders, stroke, and neurocritical care. Currently I am involved in the inpatient Intensive Care Neurology Service, inpatient and outpatient for the Stroke and Cerebrovascular Center, and outpatient general neurology clinics. I serve as the Outpatient Medical Director for the Stroke and Cerebrovascular Center that focuses on a multidisciplinary approach to optimize diagnosis and treatment. My current research also focuses on cerebrovascular disorders and stroke with specific focus on risk factors in both perinatal and childhood stroke and emotional outcomes of parents and children following pediatric stroke.

Dr. Moulin’s research focuses on the development of reliable MR sequences to measure innovative quantitative biomarkers and on the translation of these sequences into robust clinical diagnostic tools. He has a special interest in cardiac diffusion imaging, motion encoding approaches, free-breathing, and cardiac motion-compensation techniques. In his latest work, he developed an approach to combine diffusion imaging and tissue displacement imaging to estimate the local strains of the cardiac cells which can help characterize the onset and progression of cardiac pathologies.